Patent · US Expired

Method for biological cell and particulate analysis

US5581349A · kind A · utility

13Cited by
3References
16Claims
0Family size

Inventor

Key dates

Filing dateMar 27, 1995
Grant dateDec 3, 1996
Priority date
Expiry dateMar 27, 2015

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01J3/4412
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

An analytical device for detecting and analyzing the population of neutral or electrically-charged solutes, including providing a light source for producing a collimated beam, providing a solution vessel containing the sample solution to be analyzed, directing the light beam through the sample solution to thereby produce scattered light, a photomultiplier or a photon counter for detecting the scattered light, said photomultiplier being positioned at an angle to receive the scattered light from the collimated beam, an analog-to-digital converter communicating with the photomultiplier, converting the electrical signals output into a digital output, a digital correlator for receiving the digital output and to calculate a time autocorrelation function of the motion of the solutes in the fluid medium, immersing two electrodes in the solution vessel, generating an electrical field between the two electrodes, positioning the electrodes such that a field gradient is created between the electrode, and such that the light beam partially impinges on one of the electrodes to create a heterodyne effect, and an electrical field generator connected to said electrodes, producing an oscillating ele…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.