Iodine-containing fluorocarbon contrast agents
US5582813A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 27, 1994 |
| Grant date | Dec 10, 1996 |
| Priority date | — |
| Expiry date | Jan 27, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to nonterminally iodinated fluorinated compositions. The compositions, including, dispersions, emulsions, microemulsions, and gels are useful for biomedical applications, particularly radiography and scintigraphy. The compounds used in the invention preferably have the following general formula: EQU R.sub.F CH.dbd.CIR.sup.1 wherein, PA0 R.sub.F is a linear, branched, or cyclic first fluorocarbon radical, having 2 to 12 carbon atoms in which 50 to 100% of the hydrogen atoms have been replaced by fluorine atoms; and PA0 R.sup.1 is selected from the group consisting of a second fluorocarbon radical and a hydrocarbon radical, wherein, PA1 the second fluorocarbon radical is linear, branched, or cyclic, having 2 to 12 carbon atoms in which 50 to 100% of the hydrogen atoms have been replaced by fluorine atoms; and PA1 the hydrocarbon radical is linear, branched, or cyclic, having 2 to 14 carbon atoms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.