Active fractions of Cordyceps sinensis and method of isolation thereof
US5582828A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 15, 1995 |
| Grant date | Dec 10, 1996 |
| Priority date | — |
| Expiry date | Mar 15, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/645
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for identifying and isolating the active fractions in Cordyceps sinensis. It covers a findings of the structure of an active compound that is present in the active fraction, an isolation method that can be used to extract the active fractions and a specific active compound, and the use of "H1-A", one specific active compound that is present in the active fractions thus isolated, to ameliorate the clinical symptoms and renal lesions in laboratory mice with induced IgA nephropathy (Berger's disease). This work has important pharmacological implications for the suppression of activated mesangial cells and IgA nephropathy in humans.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.