Patent · US Expired

Prostaglandin E.sub.1 analogues

US5583158A · kind A · utility

0Cited by
4References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 19, 1995
Grant dateDec 10, 1996
Priority date
Expiry dateApr 19, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C405/0033
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A prostaglandin E.sub.1 analogue represented by formula ##STR1## wherein R.sup.1 represents a hydrogen atom or a C.sub.1 -C.sub.6 alkyl group; and X is an oxygen atom and R.sup.2 represents ##STR2## or X is a sulfur atom and R.sup.2 represents ##STR3## The compound has a strong and prolonged inhibitory action for platelet aggregation and is useful for treatment of various thrombotic diseases including peripheral circulatory disturbance.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.