Patent · US Expired

Nucleic acid separation on alkylated nonporous polymer beads

US5585236A · kind A · utility

80Cited by

1References

35Claims

0Family size

Assignee

Sarasep, Inc. · US

Inventors

Gunther Bonn · Zirl, AT
Christian Huber · Zwingenberg, DE
Peter Oefner · Innsbruck, AT

Key dates

Filing date	Nov 17, 1993
Grant date	Dec 17, 1996
Priority date	—
Expiry date	Nov 17, 2013

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S435/803
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

Nonporous polymer beads having an average diameter of about 1-100 microns are suitable for chromatographic separation of mixtures of nucleic acids when the polymer beads are alkylated with alkyl chains having at least three carbon atoms. The polymer beads provide efficient separation of nucleic acids using ion-pair reverse phase chromatography.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.