Derivatives of valproic acid amides and 2-valproenoic acid amides, method of making and use thereof as anticonvulsant agents
US5585358A · kind A · utility
34Cited by
1References
19Claims
0Family size
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Key dates
| Filing date | Jul 6, 1993 |
| Grant date | Dec 17, 1996 |
| Priority date | — |
| Expiry date | Jul 6, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C255/29
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound having the structure: ##STR1## wherein R.sub.1, R.sub.2, and R.sub.3 are independently the same or different and are hydrogen, a C.sub.1 -C.sub.6 alkyl group, an aralkyl group, or an aryl group, and n is an integer which is greater than or equal to 0 and less than or equal to 3. Also provided are a compound containing a 2-valproenoic moiety, pharmaceutical compositions comprising these compounds, and methods of using them for the effective treatment of epilepsy and other neurological disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.