20-position modified pharmaceutically active vitamin D series compounds

US5585368A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Andreas Steinmeyer · Berlin, DE
• Gunter Neef · Berlin, DE
• Gerald Kirsch · Berlin, DE
• Katica Schwarz · Berlin, DE
• Ruth Thieroff-Ekerdt · Concord, US
• Herbert Wiesinger · Berlin, DE
• Martin Haberey · Berlin, DE

Key dates

• Filing date: Jun 24, 1993
• Grant date: Dec 17, 1996
• Expiry date: Jun 24, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F7/1804
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to vitamin D derivatives, modified in 20-position, of general formula I ##STR1## in which X, Y, Z, R.sub.1, R.sub.2 as well as R.sub.3 have the meaning indicated in the description, process for their production and their use as agents for treatment of hyperproliferative diseases of the skin.