Reduction method for substituted 5-methylene-thiazolidinediones
US5585495A · kind A · utility
5Cited by
0References
8Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 17, 1994 |
| Grant date | Dec 17, 1996 |
| Priority date | — |
| Expiry date | Jun 17, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/34
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a method for making known pharmaceutical compounds. More particularly the present invention provides a new reduction method for making thiazolidinedione derivatives, particularly ciglitazone, pioglitazone, and englitazone. This reduction method comprises reacting a compound of the formula II with a cobalt ion, a ligand and a reducing agent to achieve a compound of the formula I. ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.