Prodrugs for antibody directed enzyme prodrug therapy
US5587161A · kind A · utility
26Cited by
1References
21Claims
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Key dates
| Filing date | Dec 21, 1994 |
| Grant date | Dec 24, 1996 |
| Priority date | — |
| Expiry date | Dec 21, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C311/51
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Prodrugs, of generic formula I, are disclosed for use in antibody directed enzyme prodrug therapy (ADEPT). The prodrugs substrates for carboxypeptidase G2 (CPG2) and yield more cytotoxic drugs than known products of CPG2 catalysed
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.