Chimeric blood coagulation proteins
US5587310A · kind A · utility
9Cited by
2References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 11, 1994 |
| Grant date | Dec 24, 1996 |
| Priority date | — |
| Expiry date | Jul 11, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Chimeric blood coagulation proteins are disclosed. The proteins are (i) coagulation factor V in which at least one A3, C1 or C2 domain exon thereof is replaced with the homologous exon of coagulation factor VIII; or (ii) coagulation factor VIII in which at least one A3, C1 or C2 domain exon thereof is replaced with the homologous exon of coagulation factor V. The chimeric proteins are useful for diagnostic purposes in epitope mapping and for therapeutic purposes in facilitating blood coagulations in patients in need of such treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.