Substituted 1,3-oxathiolanes and substituted 1,3-dithiolanes with antiviral properties
US5587480A · kind A · utility
36Cited by
5References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 20, 1994 |
| Grant date | Dec 24, 1996 |
| Priority date | — |
| Expiry date | Apr 20, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/1804
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to novel substituted 1,3-oxathiolanes and substituted 1,3-dithiolanes or pharmaceutically acceptable salts and esters thereof, of the formula: ##STR1## wherein X is S, S.dbd.O, or SO.sub.2 ; PA1 Y is O, S, S.dbd.O, or SO.sub.2 ; PA1 R.sub.1 is hydrogen, trisubstituted silyl, C.sub.1-6 alkyl, aralkyl, or C.sub.1-6 acyl, and R.sub.2 is a pyrimidine base or an analogue or derivative thereof. This invention also relates to processes for preparing these compounds, intermediates useful in their preparation, to pharmaceutical compositions containing them and to the use of these compounds as antiviral agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.