Patent · US Expired

Cultures of permanent lines of human promyelocytic cells and their uses for the screening of molecules utilizable in particular in the treatment of leukemias

US5589345A · kind A · utility

0Cited by

0References

4Claims

0Family size

Assignee

Institut National de la Sante et de la Recherche Medicale (INSERM) · FR

Inventors

Michel Lanotte · Paris, FR
Roland Berger · Nittenau, DE

Key dates

Filing date	Dec 17, 1993
Grant date	Dec 31, 1996
Priority date	—
Expiry date	Dec 17, 2013

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S436/813
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention concerns permanent cell lines of human promyelocyte cells characteristic of acute promyelocytic leukemias, these cells being cytogenetically characterized by a translocation t(15;17), capable of indefinite proliferation in a culture medium. It also concerns the use of these cell lines, particularly for screening molecules capable of inducing cell maturation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.