Expression of human protein C in mammary tissue of transgenic mammals
US5589604A · kind A · utility
27Cited by
3References
20Claims
0Family size
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Inventors
Key dates
| Filing date | May 23, 1994 |
| Grant date | Dec 31, 1996 |
| Priority date | — |
| Expiry date | May 23, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Recombinant protein C characterized by a high percentage of active protein can be obtained in the milk of transgenic mammals that incorporate DNAs according to the present invention. Transgenic mammals of the present invention are produced by introducing into developing embryos DNA that encodes protein C, such that the DNA is stably incorporated in the DNA of germ line cells of the mature mammals and inherited in normal, mendelian fashion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.