Detection of mammalian immunodeficiency viruses

US5591572A · kind A · utility

Assignees

• St. Vincent's Institute of Medical Research · AU
• Agen Limited · AU

Inventors

• Bruce E. Kemp · Melbourne, AU
• Carmel J. Hillyard · Forsayth, AU
• Dennis Rylatt · Melbourne, AU
• Peter G. Bundesen · Brisbane, AU

Key dates

• Filing date: Feb 24, 1994
• Grant date: Jan 7, 1997
• Expiry date: Feb 24, 2014

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/975
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention provides peptides having immunological properties in common with the backbone of an immunodominant region of the transmembrane envelope protein of mammalian immunodeficiency viruses, which region comprises a disulphide loop and which region is unexpectedly highly conserved in mammalian immunodeficiency viruses derived from different mammalian sources. The invention also provides method and immunoassay test kits for detection of mammalian immunodeficiency viruses using these above peptides. The invention also relates to antibodies directed against the above peptides, and their use in immunoassays and as immunoadsorbents for mammalian immunodeficiency virus.