Patent · US Expired

Transduced mesenchymal stem cells

US5591625A · kind A · utility

234Cited by
14References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 24, 1993
Grant dateJan 7, 1997
Priority date
Expiry dateNov 24, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2740/13043
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Genetically engineered human stem cells that carry within them genes of interest particularly for the expression of physiologically or pharmacologically active proteins or for use in gene therapy. In addition to correction of genetic disorders, is the ability to introduce, in a targeted manner, additional copies of essential genes to allow expression in proliferating, nondifferentiating cells of certain gene products. These genes can be, for example, hormones matrix proteins, cytokines, adhesion molecules, detoxification enzymes and "rebuilding" proteins important in tissue repair.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.