New phosphonic acid compounds
US5591728A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 3, 1995 |
| Grant date | Jan 7, 1997 |
| Priority date | — |
| Expiry date | Jul 3, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compound of formula (I): ##STR1## in which: R.sub.1 represents a hydroxyl, alkoxy or amino (unsubstituted or substituted) group, PA1 R.sub.2 represents an unsubstituted or substituted alkyl group, PA1 X.sub.1 represents --NH--, PA1 X.sub.2 represents --O--, PA1 R.sub.3 represents a hydrogen atom or an alkyl or phenyl group, PA1 R.sub.4 represents an alkyl group which is always substituted with one or more hydroxyl, benzyloxy, benzyloxycarbonylamino, amino, mono- or dialkylamino, acetoxy or 2,2-dimethyl-1,3-dioxolan-4-yl groups, such groups being identical or different, PA1 R.sub.5 represents a 3-indolylmethyl, naphthylmethyl, alkyl, phenyl or benzyl group, its isomers as well as its addition salts with a pharmaceutically acceptable acid or base, and medicinal products containing the same are useful as endothelin convertase inhibitor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.