Patent · US Expired

N-[Mercaptoacyl (amino acid or peptide ) ] compounds and S-lipophiIic aliphatic carbonyl derivatives thereof as antihypertensives

US5591891A · kind A · utility

11Cited by

10References

14Claims

0Family size

Assignee

Institut National de la Sante et de la Recherche Medicale (INSERM) · FR

Inventors

Marie-Claude Fournie-Zaluski · Paris, FR
Bernard Roques · Paris, FR

Key dates

Filing date	Jan 24, 1994
Grant date	Jan 7, 1997
Priority date	—
Expiry date	Jan 24, 2014

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C2603/74
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

N-[Mercaptoacyl(amino acid or peptide)] compounds and S-lipophilic aliphatic carbonyl derivatives thereof, and pharmaceutical compositions comprising such compounds, as well as the use of these compounds as antihypertensives by the inhibition of neutral endopeptidase and/or peptidyldipeptidase A are disclosed. Methods for preparing the such compounds and derivatives are disclosed also.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.