Tissue implant systems and methods for sustaining viable high cell densities within a host
US5593440A · kind A · utility
359Cited by
52References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 23, 1994 |
| Grant date | Jan 14, 1997 |
| Priority date | — |
| Expiry date | May 23, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B5/14532
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for implanting cells is disclosed which employs a chamber having a wall forming porous boundary between the host and implanted cells. According to the method, a given number of cells (N) is placed within the porous boundary of a given area (A) such that the quantity A/N is less than about 200 .mu.m.sup.2 /cell. The porous boundary has a pore size, an ultimate strength, and a metabolic transit value that assures the survival of the cells during the critical ischemic period and afterward.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.