Process for the preparation of enantiometric 2-alkanoic acid amides from nitriles
US5593871A · kind A · utility
9Cited by
13References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 15, 1995 |
| Grant date | Jan 14, 1997 |
| Priority date | — |
| Expiry date | Feb 15, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/38
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention relates to the enantioselective biologically-catalyzed hydrolysis of certain racemic nitriles to the corresponding R- or S-amides, chemically or biologically-catalyzed hydrolysis of the amides to the corresponding R- or S-acids in a batch process or in a continuous process that employs racemization and recycling of enantiomeric nitrile intermediates, the racemic nitriles being selected from the group, A--C(R.sup.1)(R.sup.2)CN, wherein A, R.sup.1 and R.sup.2 are as defined in the text, as well as certain biological materials employed to catalyze the process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.