Oncoprotein protein kinase
US5593884A · kind A · utility
18Cited by
0References
8Claims
0Family size
Inventors
Key dates
| Filing date | Jul 18, 1994 |
| Grant date | Jan 14, 1997 |
| Priority date | — |
| Expiry date | Jul 18, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An isolated polypeptide (JNK) characterized by having a molecular weight of 46kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.