Chimeric protein comprising an RTX-family cytotoxin and interferon-2 or interferon
US5594107A · kind A · utility
13Cited by
17References
13Claims
0Family size
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Key dates
| Filing date | Dec 20, 1993 |
| Grant date | Jan 14, 1997 |
| Priority date | — |
| Expiry date | Dec 20, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/825
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New chimeric proteins, DNA encoding the same, and the use of these proteins in stimulating immunity against respiratory diseases such as pneumonia, including shipping fever pneumonia, are disclosed. The chimeric proteins include at least one epitope of an RTX cytotoxin fused to an active fragment of a cytokine. The chimeric proteins can be used in a vaccine composition. Also disclosed are methods of vaccination as well as methods of making the proteins employed in the vaccines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.