Nucleic acids encoding microsomal trigyceride transfer protein
US5595872A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 3, 1993 |
| Grant date | Jan 21, 1997 |
| Priority date | — |
| Expiry date | Sep 3, 2013 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/044
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Nucleic acid sequences, particularly DNA sequences, coding for all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, expression vectors containing the DNA sequences, host cells containing the expression vectors, and methods utilizing these materials. The invention also concerns polypeptide molecules comprising all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, and methods for producing these polypeptide molecules. The invention additionally concerns novel methods for preventing, stabilizing or causing regression of atherosclerosis and therapeutic agents having such activity. The invention concerns further novel methods for lowering serum liquid levels and therapeutic agents having such activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.