4-aryl-3-(heteroarylureido)quinoline derivatves
US5596001A · kind A · utility
35Cited by
4References
11Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 25, 1993 |
| Grant date | Jan 21, 1997 |
| Priority date | — |
| Expiry date | Oct 25, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D215/38
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula ##STR1## and the pharmaceutically acceptable salts thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, m, X and Q are as defined below, and novel intermediates used in the synthesis of such compounds. The compounds of formula I are inhibitors of acyl coenzyme A: cholesterol acyltransferase (ACAT) and are useful as hypolipidemic and natiatherosclerosis agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.