DNA Encoding the human P.sub.2U receptor and null cells expressing P.sub.2U receptors

US5596088A · kind A · utility

Assignees

• The University of North Carolina at Chapel Hill · US
• The Curators of the University of Missouri · US

Inventors

• Richard C. Boucher, Jr. · Chapel Hill, US
• Gary A. Weisman · Columbia, US
• John T. Turner · Ashland, US
• Thomas K. Harden · Westfield, US
• Claude E. Parr · Chapel Hill, US
• Daniel M. Sullivan · Lutz, US
• Laura J. Erb · Columbia, US
• Kevin D. Lustig · Cambridge, US

Key dates

• Filing date: May 16, 1995
• Grant date: Jan 21, 1997
• Expiry date: May 16, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Isolated DNAs encoding the human P.sub.2U receptor are disclosed, along with vectors and host cells containing the same and methods of using the same. Host cells which are essentially free of endogenous P.sub.2U receptor expression, and which express a heterologous P.sub.2U receptor such as a murine P.sub.2U receptor, are also disclosed, along with methods of using the same.