Ruthenium-phosphine complex catalysts for asymmetric hydrogenations
US5596113A · kind A · utility
4Cited by
2References
3Claims
0Family size
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Key dates
| Filing date | May 18, 1995 |
| Grant date | Jan 21, 1997 |
| Priority date | — |
| Expiry date | May 18, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D207/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
.beta.- or .gamma.-Ketoesters and .beta.- or .gamma.-ketoamides are asymmetrically reduced with a Ru(II)-BINAP derived catalyst at about 40.degree. C. and about 50 N/mm.sup.2 of hydrogen in the presence of a strong acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.