Patent · US Expired

System and method for forming synthetic protein crystals to determine the conformational structure by crystallography

US5597457A · kind A · utility

27Cited by

2References

10Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

George D. Craig · Lafayette, US
Robert S. Glass · Livermore, US
Bernhard Rupp · Eppingen, DE

Key dates

Filing date	Apr 8, 1996
Grant date	Jan 28, 1997
Priority date	—
Expiry date	Apr 8, 2016

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC30B29/58
WIPO fieldSurface technology, coating
WIPO sectorChemistry

Abstract

A method for forming synthetic crystals of proteins in a carrier fluid by use of the dipole moments of protein macromolecules that self-align in the Helmholtz layer adjacent to an electrode. The voltage gradients of such layers easily exceed 10.sup.6 V/m. The synthetic protein crystals are subjected to x-ray crystallography to determine the conformational structure of the protein involved.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.