Process for prefilling and terminally sterilizing syringes
US5597530A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 26, 1996 |
| Grant date | Jan 28, 1997 |
| Priority date | — |
| Expiry date | Apr 26, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M5/002
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method of prefilling and terminally sterilizing a syringe including providing a syringe barrel having first and second opposite ends where the first end includes a port therethrough with a connector member formed about an exterior of the port and the second end being open. Particulate matter is removed from the interior of the syringe barrel and a cap and stopper are sterilized, the stopper including first and second opposite longitudinal ends. The first end of the stopper is inserted into the second open end of the syringe barrel until the first end of the stopper reaches the first end of the syringe barrel. The syringe barrel then is filled with a desired liquid, such as a medicament or imaging agent, through the port of the first end of the syringe barrel so that substantially no air enters the syringe barrel and where the stopper moves within the syringe barrel from the first to the second ends thereof upon filling. The cap then is connected to the connector member of the first end of the syringe barrel to seal the port and then the syringe barrel, stopper, luer cap and liquid within the syringe barrel are terminally sterilized in a autoclave having a spray over-pressure cycl…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.