Humanized monoclonal antibodies against human interleukin-4
US5597710A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 10, 1994 |
| Grant date | Jan 28, 1997 |
| Priority date | — |
| Expiry date | Mar 10, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Humanized monoclonal antibodies are provided which are specific for human IL-4 and have properties unexpectedly superior to other, previously available humanized antibodies. Also provided are nucleic acids which encode the heavy and light chain variable regions of such monoclonal antibodies or antigenic fragments thereof; anti-idiotypic antibodies; and methods for detecting, measuring and immunopurifying human IL-4, and for blocking or mimicking the biological activity of human IL-4.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.