Monoclonal antibodies reactive with a human atheroma associated antigen
US5597726A · kind A · utility
9Cited by
6References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 30, 1995 |
| Grant date | Jan 28, 1997 |
| Priority date | — |
| Expiry date | Mar 30, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/83
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a naturally occurring, minimally modified LDL antigen which is present in human atherosclerotic lesions as well as in the serum of a high percentage of patients with coronary artery disease. The invention also comprises antibodies reactive with the antigen, hybridoma cell lines that produce the antibodies of the invention, and methods for using the antibodies in the diagnosis and treatment of atherosclerotic disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.