Phenothiazine cytokine inhibitors
US5597819A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 13, 1995 |
| Grant date | Jan 28, 1997 |
| Priority date | — |
| Expiry date | Feb 13, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New benzothiazine derivatives corresponding to the general formula I: ##STR1## in which: X represents halogen, PA1 n represents 0, 1, or 2, PA1 B represents the following formula: ##STR2## in which: R.sub.1 & R.sub.2 together with the carbons to which they are attached form a 6-carbon-atom aromatic ring which is optionally substituted by a group X' representing halogen, and PA1 Y represents the radical --(SO.sub.2).sub.x --Alk--Z, x, Alk, and Z are as defined in the specification; as well as their possible stereoisomers, epimers, N-oxides and pharmaceutically-acceptable acid or base addition salts; and medicinal products containing the same, useful in the treatment of inflammatory disorders requiring an inhibitor of cytokines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.