Patent · US Expired

Lactone stable formulation of camptothecin and methods for uses thereof

US5597829A · kind A · utility

12Cited by
21References
39Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 9, 1994
Grant dateJan 28, 1997
Priority date
Expiry dateMay 9, 2014

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/1075
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Camptothecin (CPT) an anticancer drug is poorly soluble in water. This invention overcomes this limitation by teaching novel pharmaceutically acceptable lactone stable CPT formulations for the direct administration of CPT to human subjects with cancer. The claimed invention also describes novel dosages, schedules, and routes of administration of the lactone stable CPT formulations to patients with various forms of cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.