Phospholipase A.sub.2 inhibitor
US5597943A · kind A · utility
1Cited by
1References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 13, 1995 |
| Grant date | Jan 28, 1997 |
| Priority date | — |
| Expiry date | Dec 13, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D309/38
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to the new thielocin derivatives, which exhibit phospholipase A.sub.2 inhibitory activity of the formula: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, and R.sup.8 are independently hydrogen, lower alkyl, lower alkoxy, hydroxy, or halogen; PA1 E.sub.1 and E.sub.2 are independently hydrogen, or an ester residue; PA1 m and n are independently an integer of 0 to 4; PA1 --Y-- is a bivalent group which is selected from the group consisiting of the following radicals: ##STR2## or the salts thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.