Immunogenic four amino acid epitope against Plasmodium vivax
US5599543A · kind A · utility
1Cited by
5References
12Claims
0Family size
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Key dates
| Filing date | Mar 9, 1992 |
| Grant date | Feb 4, 1997 |
| Priority date | — |
| Expiry date | Mar 9, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An agent and pharmaceutical formulations of the agent containing a synthetic peptide of the human malaria Plasmodium vivax, containing at least one repeat of a synthetic peptide having the amino acid sequence Ala-Gly-Asp-Arg (AGDR) which is a protective epitope found on the circumsporozoite (CS) protein of the sporozoites of the human malaria Plasmodium vivax. When a monoclonal antibody specific for this four amino acid sequence binds to the CS protein of the P. vivax sporozoite in vivo, infection is prevented.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.