Patent · US Expired

Reagent for measuring direct bilirubin

US5599661A · kind A · utility

3Cited by
8References
9Claims
0Family size

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Inventors

Key dates

Filing dateDec 28, 1994
Grant dateFeb 4, 1997
Priority date
Expiry dateDec 28, 2014

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/146666
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A reagent system and method are described for optically measuring direct bilirubin by the reaction of a bilirubin oxidase, oxidizing agent or diazonium salt, with the direct bilirubin, wherein a tetrapyrrole compound is provided in the presence of the bilirubin oxidase, oxidizing agent or diazonium salt. It is possible to accurately measure the direct bilirubin, which is known to increase considerably in the biological fluids of patients having obstructive jaundice, etc. The reagent system and method are useful in clinical settings, etc.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.