Reagent for measuring direct bilirubin
US5599661A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Dec 28, 1994 |
| Grant date | Feb 4, 1997 |
| Priority date | — |
| Expiry date | Dec 28, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/146666
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A reagent system and method are described for optically measuring direct bilirubin by the reaction of a bilirubin oxidase, oxidizing agent or diazonium salt, with the direct bilirubin, wherein a tetrapyrrole compound is provided in the presence of the bilirubin oxidase, oxidizing agent or diazonium salt. It is possible to accurately measure the direct bilirubin, which is known to increase considerably in the biological fluids of patients having obstructive jaundice, etc. The reagent system and method are useful in clinical settings, etc.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.