Method for isolating a novel receptor for .alpha.4 integrins
US5599676A · kind A · utility
21Cited by
0References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 14, 1994 |
| Grant date | Feb 4, 1997 |
| Priority date | — |
| Expiry date | Oct 14, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention is directed to a method for isolating a novel receptor for .alpha.4 integrins such as VLA-4, that is distinct from VCAM-1 and from fibronectin. Isolated nucleic acids encoding the receptor and antibodies to the receptor are also provided. The invention is also directed to pharmaceutical compositions, and methods of treating disorders involving an undesirable inflammatory or immune response by administering the VLA-4 receptor of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.