Sulphorous derivatives of imidazole and their use as medicaments
US5599830A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 9, 1995 |
| Grant date | Feb 4, 1997 |
| Priority date | — |
| Expiry date | Jan 9, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D233/90
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the products: ##STR1## in which: R.sub.1 =alkyl, alkenyl, alkynyl, alkylthio, PA0 R.sub.2B, R.sub.3B representing: PA1 hydrogen, mercapto, formyl, acyl, carboxy nitro, cyano, PA1 --PO.sub.3 (R).sub.2, R representing hydrogen, alkyl, aryl, amino or carbamoyl, PA1 the R.sub.4B radicals; ##STR2## n=0 to 2 X'=aryl PA0 R.sub.4B either represents --(CH.sub.2).sub.m1 --S(O).sub.m2 --X--R.sub.10, m1=0 to 4, m2=0 to 2 either m1 is different from 0, X--R.sub.10 represents amino, or whatever m1 is, X represents a single bond or --NH--, --NH--CO--, --NH--CO--NH--, PA0 R.sub.10 =alkyl, alkenyl or aryl, or hydrogen, alkyl, alkenyl, alkynyl, acyl or amino, PA1 --S--S--R.sub.4B ', R.sub.4B ' represents R.sub.4B except for amino and alkoxy, and one of R.sub.2B and R.sub.3B represents --OR.sub.4B : ##STR3## m=0 to 2, Y.sub.B ---Y.sub.1B --B--Y.sub.2B, PA0 Y.sub.1B =aryl, PA0 B=a single bond or --CO--, --O--, --NH--CO--, --CO--NH--, --O--O--(CH.sub.2).sub.p --, PA0 p=1 to 3, PA0 Y.sub.2B represents hydrogen, cyano, carboxy, in all isomer forms and salts, their use as medicaments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.