Process for the preparation of 2-fluorophenylhydrazine
US5599992A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jan 22, 1996 |
| Grant date | Feb 4, 1997 |
| Priority date | — |
| Expiry date | Jan 22, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C241/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a process for the preparation of 2-fluorophenylhydrazine or 2-fluorophenylhydrazine hydrochloride, which comprises diazotizing 2-fluoroaniline, reducing the resulting diazonium salt with alkaline bisulfite solution to give 2-fluorophenylhydrazine .alpha..beta.-disulfonate, hydrolyzing the latter with hydrochloric acid to give 2-fluorophenylhydrazine hydrochloride, adding alkali metal solution to neutralize the mixture, subsequently cooling the mixture, removing the 2-fluorophenylhydrazine precipitate by filtration and, if appropriate, reacting the latter with hydrochloric acid to give 2-fluorophenylhydrazine hydrochloride.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.