Partially delipidated D25 polysaccaride composition for imaging and diagnosis
US5601799A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 6, 1995 |
| Grant date | Feb 11, 1997 |
| Priority date | — |
| Expiry date | Jan 6, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a D 25 polysaccharide compound whose lipid has been partially removed and to its derivatives, wherein at least 85% by weight, preferably 90% of the compound, exists in aqueous solution in monomeric form. The 30 kD molecular weight polysaccharide compound extracted from the membrane proteoglycan of the bacterium Klebsiella pneumoniae is mentioned in particular. The amount of palmitic fatty acids which is bound to it in esterified form does not exceed 0.01% by weight of the compound and the amount of palmitic fatty acids which is associated with it in the free form does not exceed 0.1% by weight of the compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.