Patent · US Expired

.gamma., .delta. T cell receptor and methods for detection

US5601822A · kind A · utility

4Cited by
7References
26Claims
0Family size

Assignees

Inventors

Key dates

Filing dateNov 19, 1993
Grant dateFeb 11, 1997
Priority date
Expiry dateNov 19, 2013

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/868
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The present invention provides purified polypeptides which comprise at least a portion of a .delta. T cell receptor polypeptide, a .gamma. T cell receptor polypeptide, a .gamma., .delta. T cell receptor complex or a .gamma., .gamma. T cell receptor complex. Substances capable of forming complexes with these polypeptides are also provided. Additionally, methods for detecting T cells which have within them or on their surfaces a polypeptide of the present invention are provided. Moreover, methods for diagnosing immune system abnormalities are provided which comprise measuring in a sample from a subject the number of T cells which have within them or on their surfaces a polypeptide of the present invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.