Peptide library formats and methods relating thereto
US5601992A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 9, 1994 |
| Grant date | Feb 11, 1997 |
| Priority date | — |
| Expiry date | Sep 9, 2014 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2410/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for detecting the interaction between an oligomeric molecule and a target is provided. A plurality of beads is applied to a substrate, each bead having associated therewith multiple copies of only a single oligomeric molecule. The beads are substantially spaced-apart from one another and are substantially immobilized on the substrate. Conditions are applied such that a substantial portion of the multiple copies associated with each bead can disassociate from and diffuse into the substrate, the substrate constructed and arranged to permit only substantially localized diffusion. A localized signal occurring as a result of the diffusion is detected. Coated beads and libraries of coated beads also are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.