Method and apparatus for magnetically separating biological particles from a mixture
US5602042A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Apr 14, 1994 |
| Grant date | Feb 11, 1997 |
| Priority date | — |
| Expiry date | Apr 14, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/824
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An apparatus and method provide automated collection and transfer of particles from a liquid suspension to a glass slide for visual examination. A magnet is positioned adjacent to a solution which contains particles tagged with magnetic beads, for example cells, so that the magnetic particles flow toward the magnet and collect against a collection surface positioned between the particles and the magnet. A transfer mechanism applies a selected pressure to a second side of the collection surface for transferring collected cells to a viewing slide. The apparatus includes a device for dispersing the liquid suspension of particles prior to the collection process and for collecting particles against the collection surface with a spatial distribution advantageous for visual examination. The transfer operation maintains this spatial distribution. The cell-dispersing device and the collection surface are on a common structure, for unitary movement, and which is readily disposable and replaceable for each sample of particles
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.