3-heteroaryl-1-pyrrolidinealkylthiols and derivatives thereof and their therapeutic utility

US5602159A · kind A · utility

Assignee

• Hoechst Roussel Pharmaceuticals · US

Inventors

• Edward J. Glamkowski · Hackettstown, US
• Yulin Chiang · Clay, US
• Joseph T. Strupczewski · Flemington, US
• Kenneth J. Bordeau · Myerstown, US
• Peter A. Nemoto · Raritan, US
• John J. Tegeler · Bound Brook, US

Key dates

• Filing date: Jun 6, 1995
• Grant date: Feb 11, 1997
• Expiry date: Jun 6, 2015

Classification

• Technology area (CPC —): General

Abstract

Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. Depot derivatives of the compounds are useful for providing long acting effects of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.