Substituted benzene derivatives useful as neuraminidase inhibitors
US5602277A · kind A · utility
24Cited by
3References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 30, 1995 |
| Grant date | Feb 11, 1997 |
| Priority date | — |
| Expiry date | Mar 30, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/3834
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound of the Formula (I): ##STR1## or pharmaceutically-suitable salts or prodrug forms thereof, wherein: n is 0-1; PA1 m is 0; PA1 p is 0-1; PA1 R.sup.1 is --CO.sub.2 H; PA1 R.sup.2 is selected from the group consisting of H, --OH, and --NH.sub.2 ; PA1 R.sup.3 is H; PA1 R.sup.4 is --C(O)NHR.sup.8 ; PA1 R.sup.5 is --NHC(R.sup.6)NH.sub.2 PA1 R.sup.6 is selected from the group consisting of .dbd.NH, .dbd.NOH, .dbd.NCN, .dbd.O, and .dbd.S; and PA1 R.sup.8 is selected from the group consisting of C.sub.1 -C.sub.4 linear or branched alkyl substituted with 0-3 halogens on each carbon.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.