Cis-acting repression sequences, cis-acting antirepression sequences, vectors, methods of preparation and use
US5604114A · kind A · utility
8Cited by
1References
27Claims
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Key dates
| Filing date | Apr 2, 1993 |
| Grant date | Feb 18, 1997 |
| Priority date | — |
| Expiry date | Apr 2, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16322
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Cis-acting repression sequences which are able to provide a cis-acting inhibitory effect on the expression of a gene when placed downstream of the gene in its untranslated message are dislcosed. Cis-acting anti-repression sequences which can relieve the cis-acting repression in the presence of the art gene product are also disclosed. These sequences correspond to a sufficient number of nucleotides from the HIV-I, HIV-2, STLV-3 or HTLV-IV genomes to provide the repression or anti-repression effects. The use of the sequences in vectors and systems to control the expression of a desired gene product is also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.