Patent · US Expired

Octahydronaphthalene oxime derivatives for cholesterol biosynthesis inhibition

US5604256A · kind A · utility

2Cited by
1References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 14, 1994
Grant dateFeb 18, 1997
Priority date
Expiry dateDec 14, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12R2001/80
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of formula (I): ##STR1## (in which: R is hydrogen, methyl or hydroxy; X is alkyl, alkenyl, cycloalkyl, aryl, aralkyl, or a heterocyclic group; A is a single bond, or an alkylene, alkenylene, alkynylene or alkadienylene group; Y is hydrogen, aryl, cycloalkyl or a heterocyclic group) have the ability to inhibit the biosynthesis of cholesterol, and can thus be used for the treatment and prophylaxis of diseases relating to high blood cholesterol levels.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.