Cephalosporin antibiotics and processes for preparation thereof
US5605895A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 20, 1994 |
| Grant date | Feb 25, 1997 |
| Priority date | — |
| Expiry date | Jul 20, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a cephalosporin compound represented by the following general formula (I), its pharmaceutically acceptable non-toxic salt, physiologically hydrolyzable ester, hydrate or solvate, or isomers thereof, which is useful as an antibiotic agent: ##STR1## in which R.sup.1 represents hydrogen or an amino-protecting group, PA1 R.sup.2 and R.sup.3 can be identical or different and each represent hydrogen or a hydroxy-protecting group, or PA1 R.sup.2 and R.sup.3 together can form a diol-protecting cyclic group, PA1 R.sup.4 represents hydrogen or a carboxyl-protecting group, PA1 R.sup.5 represents hydrogen, C.sub.1-4 alkyl, alkoxycarbonyl, carboxyl or sulfomethyl, PA1 R.sup.6 represents hydrogen, amino or substituted amino, and PA1 R.sup.7 represents C.sub.1-4 alkyl, amino or substituted amino, or PA1 R.sup.5 and R.sup.6 together with the carbon atoms to which they are attached can form a 3 to 7-membered cyclic group, or PA1 R.sup.6 and R.sup.7 together with the carbon and nitrogen atoms to which they are attached can form a 3 to 7-membered heterocyclic ring which may optionally contain additional heteroatoms such as nitrogen and/or oxygen and which may be subst…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.