Bicyclic heterocyclic derivatives having .alpha..sub.1 adrenergic and 5HT.sub.1A activities

US5605896A · kind A · utility

Assignee

• Recordati S.A. Chemical and Pharmaceutical Company · CH

Inventors

• Amedeo Leonardi · Milano, IT
• Gianni Motta · Barlassina, IT
• Carlo Riva · Milano, IT
• Rodolfo Testa · Milano, IT

Key dates

• Filing date: Aug 31, 1994
• Grant date: Feb 25, 1997
• Expiry date: Aug 31, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/65586
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention provides bicyclic heterocyclic derivatives and their pharmaceutically acceptable salts useful for the treatment of hypertension, urethral and lower urinary tract contractions, and other disorders. The compounds are also useful for binding .alpha..sub.1 -adrenergic and 5HT.sub.1A serotonergic receptors, in vitro or in vivo.