Amphiphilic polyene macrolide antibiotic compounds
US5606038A · kind A · utility
34Cited by
1References
14Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 10, 1995 |
| Grant date | Feb 25, 1997 |
| Priority date | — |
| Expiry date | Apr 10, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/01
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Described herein is a method, and the resulting compound, for the synthesis of improved amphiphilic antibiotic agents achieved by altering the chemical structure of amphiphilic polyene macrolide compounds with an oligo(ethylene glycol) conjugate in order to raise the critical micelle concentration of the compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.