Nucleic acid probes and methods
US5606045A · kind A · utility
17Cited by
2References
34Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 21, 1993 |
| Grant date | Feb 25, 1997 |
| Priority date | — |
| Expiry date | Apr 21, 2013 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/19
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to compositions comprising an oligonucleotide linked to a detectably labeled marker component comprising a fluorophore moiety which comprises a substantially planar, multidentate macrocyclic ligand coordinated to a central atom capable of coordinating with two axial ligands and two polyoxyhydrocarbyl moieties which are attached as axial ligands to the central atom. The present invention is also directed to nucleic acid hybridization and amplification methods employing such compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.