Heterocyclic-fused lactams promote release of growth hormone

US5606054A · kind A · utility

Assignee

• MERCK & CO., INC. · US

Inventors

• Michael H. Fisher · Bound Brook, US
• Helmut Mrozik · Matawan, US
• William R. Schoen · Edison, US
• Thomas L. Shih · Edison, US
• Matthew J. Wyvratt · Mountainside, US

Key dates

• Filing date: Dec 14, 1993
• Grant date: Feb 25, 1997
• Expiry date: Dec 14, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D495/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

There are disclosed certain novel compounds identified as heterocyclic-fused lactams which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to increase the stature of those afflicted with a lack of a normal secretion of natural growth hormone. Growth promoting compositions containing such heterocyclic-fused lactams as the active ingredient thereof are also disclosed.